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Determination of particle size distribution — Single particle light interaction methods — Part 1: Light scattering aerosol spectrometer
This document specifies characteristics of a light scattering aerosol spectrometer (LSAS) which is used for measuring the size, number concentration and number-based size distribution of particles suspended in a gas. This document provide the calibration procedure and the validation method for aerosol spectrometers.
This document applies to:
— characterization of metered dose inhalers (MDI), dry powder inhalers (DPI) and nebulizers in pharmacy;
— production control of active agents;
— cut-off determination: impactors, cyclones and impingers;
— atmospheric aerosols: bio-aerosols, stables or composting facilities, nebulized droplets, measurements in street tunnels;
— fractional separation efficiency determination of filters.
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